Discover Your Perfect Mayesville Vacation Homes

Best Vacation Homes in Mayesville

10.0
Exceptional
(1 Review)
500 ft² 3 Guests 1 Bedroom 1 Bathroom
Family Friendly Apartment
  • Private Pool
  • Fireplace/Heating
  • Pool
US $140/Night For 7 Nights US $979
9.7
Exceptional
(63 Reviews)
326.5 ft² 6 Guests 3 Bedrooms 3 Bathrooms
Free Cancellation Bed & Breakfast
  • Fireplace/Heating
  • Balcony/Terrace
  • View
US $172/Night For 7 Nights US $1,206
10.0
Exceptional
(293 Reviews)
1 Bedroom 1 Bathroom
Family Friendly Bed & Breakfast
  • Fireplace/Heating
  • Balcony/Terrace
  • Breakfast
US $129/Night For 7 Nights US $906
4.0
Average
(1 Review)
4 Guests 1 Bedroom 1 Bathroom
Couples Retreat House
  • Fireplace/Heating
  • Air Conditioner
  • Internet
US $179/Night For 7 Nights US $1,254
New
1399.31 ft² 6 Guests 1 Bedroom 3 Bathrooms
Free Cancellation House
  • Fireplace/Heating
  • Parking
  • Internet
US $255/Night For 7 Nights US $1,783
New
6 Guests 1 Bedroom 1 Bathroom
Pet Friendly House
  • Fireplace/Heating
  • Pet Friendly
  • Internet
US $134/Night For 7 Nights US $935
10.0
Exceptional
(3 Reviews)
1700 ft² 8 Guests 3 Bedrooms 2 Bathrooms
Family Friendly House
  • Fireplace/Heating
  • Balcony/Terrace
  • Pet Friendly
US $272/Night For 7 Nights US $1,901
10.0
Exceptional
(2 Reviews)
6 Guests 3 Bedrooms 1 Bathroom
Family Friendly House
  • Fireplace/Heating
  • Balcony/Terrace
  • Kitchen
US $99/Night For 7 Nights US $693

Mayesville Luxury Rentals

10.0
Exceptional
(1 Review)
1379 ft² 3 Bedrooms 2 Bathrooms
Family Friendly House
  • Fireplace/Heating
  • Kitchen
  • Parking
US $445/Night For 7 Nights US $3,116
10.0
Exceptional
(14 Reviews)
1 Bathroom
Family Friendly Hotel
  • Pool
  • Balcony/Terrace
  • Breakfast
US $414/Night For 7 Nights US $2,901
New
12 Guests 3 Bedrooms 1 Bathroom
Group Friendly House
  • Fireplace/Heating
  • Air Conditioner
  • Internet
US $357/Night For 7 Nights US $2,501
9.4
Exceptional
(460 Reviews)
1 Bathroom
Family Friendly Hotel
  • Spa
  • Pool
  • Breakfast
US $352/Night For 7 Nights US $2,462
7.4
Very Good
(6 Reviews)
1 Bathroom
Free Cancellation Hotel
US $299/Night For 7 Nights US $2,093
New
2500 ft² 2 Guests 1 Bedroom 1 Bathroom
Family Friendly Other
  • Fireplace/Heating
  • Pool
  • Kitchen
US $295/Night For 7 Nights US $2,066
7.0
Very Good
(32 Reviews)
1 Bathroom
Couples Retreat Hotel
  • Pool
  • Breakfast
  • Parking
US $231/Night For 7 Nights US $1,616
8.1
Excellent
(366 Reviews)
355.21 ft² 1 Bathroom
Family Friendly Hotel
  • Private Pool
  • Pool
  • Balcony/Terrace
US $227/Night For 7 Nights US $1,586

Mayesville Pet Friendly Vacation Rentals

9.8
Exceptional
(55 Reviews)
1350 ft² 6 Guests 3 Bedrooms 2 Bathrooms
Family Friendly House
  • Fireplace/Heating
  • Pet Friendly
  • Kitchen
US $152/Night For 7 Nights US $1,061
8.5
Fabulous
(376 Reviews)
357.6 ft² 9 Bathrooms
Hotel
  • Pool
  • Breakfast
  • Pet Friendly
US $132/Night For 7 Nights US $922
6.6
Good
(295 Reviews)
1 Bathroom
Family Friendly Hotel
  • Fireplace/Heating
  • Pet Friendly
  • Kitchen
US $129/Night For 7 Nights US $902
8.8
Fabulous
(3 Reviews)
8 Guests 3 Bedrooms 2 Bathrooms
Pet Friendly House
  • Fireplace/Heating
  • Pet Friendly
  • Air Conditioner
US $147/Night For 7 Nights US $1,027
8.5
Fabulous
(192 Reviews)
376.74 ft² 1 Bathroom
Family Friendly Hotel
  • Fireplace/Heating
  • Pool
  • Balcony/Terrace
US $130/Night For 7 Nights US $909
10.0
Exceptional
(12 Reviews)
4 Guests 2 Bedrooms 1 Bathroom
Family Friendly House
  • Fireplace/Heating
  • Pet Friendly
  • Kitchen
US $137/Night For 7 Nights US $956
New
1728 ft² 6 Guests 3 Bedrooms 2 Bathrooms
Family Friendly House
  • Pet Friendly
  • Kitchen
  • Air Conditioner
US $147/Night For 7 Nights US $1,029
8.0
Excellent
(3 Reviews)
5 Guests 3 Bedrooms 1 Bathroom
Ocean View House
  • Fireplace/Heating
  • Pool
  • Ocean View
US $150/Night For 7 Nights US $1,050

Mayesville Large Vacation Homes

New
4500 ft² 10 Guests 5 Bedrooms 5 Bathrooms
Family Friendly House
  • Private Pool
  • Pool
  • Pet Friendly
US $351/Night For 7 Nights US $2,457
New
12 Guests 3 Bedrooms 1 Bathroom
Family Friendly House
  • Fireplace/Heating
  • Air Conditioner
  • Internet
US $251/Night For 7 Nights US $1,758

Why Choose Rent By Owner for your Mayesville Vacation Rental Homes?

What makes our Vacation Rentals special?

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Verified Listings
Book with confidence knowing every property meets our quality and safety standards.
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Unbeatable Value
Enjoy competitive pricing with no hidden fees, providing exceptional value for every stay.
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Diverse Options
From cozy cabins to luxurious villas, find a rental that suits your style and needs.

Best Times to Visit Mayesville

When should you plan your Vacation Rentals stay?

Choosing the ideal time to visit here can enhance your experience, as the region offers charming weather and local events that make Mayesville a perfect destination for relaxing getaways throughout the late spring months.

Peak Season Highlights

spring
Spring (March to May)

During the spring months, the area experiences a vibrant atmosphere ideal for outdoor activities and exploring local scenery. Booking your vacation rental now ensures you enjoy the full beauty of this destination's blooming landscape.

Average Temperature Daytime: 75°F - Nighttime: 55°F
autumn
Fall (September to November)

The fall season offers mild weather and colorful foliage, making it a delightful time to stay in this region. Securing your rental during these months allows for a comfortable and scenic retreat.

Average Temperature Daytime: 70°F - Nighttime: 50°F

Off-Season Highlights

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Summer (June to August)

Summer brings warmer temperatures and a lively atmosphere, perfect if you're looking for a warm-weather getaway. However, accommodations may be more available during this quieter period.

Average Temperature Daytime: 88°F - Nighttime: 68°F
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Winter (December to February)

Winter months tend to be cooler and less crowded, offering a peaceful environment for those seeking tranquility. This is an ideal time for budget-conscious travelers to find more affordable vacation rentals.

Average Temperature Daytime: 55°F - Nighttime: 35°F

Weekly Weather Forecast for Mayesville

Booking Steps

01

Search Properties

Use our filters to find the right property that fits your needs.
02

Select a Rental

Click on your preferred listing to view details, amenities, and pricing.
03

Book Online

Follow the link to finalize your reservation directly on the partner’s website.

Indoor Features

  • Fully-equipped kitchens with modern appliances
  • Comfortable living areas with flat-screen TVs
  • Free Wi-Fi for staying connected
  • Air conditioning and heating for year-round comfort
  • In-unit washers and dryers for convenience
  • Luxurious bedrooms with premium bedding
  • Spa-like bathrooms with soaking tubs or walk-in showers

Outdoor Amenities

  • Enjoy outdoor grilling with a fully equipped barbecue area, perfect for hosting family cookouts in the region.
  • Relax on a spacious patio or deck that provides scenic views of the surrounding natural beauty.
  • Take advantage of a private swimming pool to cool off during warm summer days here.
  • Explore nearby walking or biking trails that showcase the area's lush landscape and local wildlife.
  • Unwind by a cozy outdoor fireplace, ideal for gatherings during cooler evenings in this destination.
  • Make use of a well-maintained yard that offers ample space for outdoor games and activities.
  • Access to a tranquil dock or waterfront area if your rental is near water bodies typical of this region.
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Family Activities

  • Mayesville Heritage Museum Tour: Dive into the rich local history at this charming museum, offering engaging exhibits perfect for family learning experiences.
  • Cricket Hill Nature Preserve: Explore scenic trails and picnic spots here, providing an ideal outdoor setting for a family day immersed in nature within the region.
  • Fishing at Lake Mayesville: Relax and bond with your loved ones by trying your luck at fishing in the tranquil waters of this nearby lake.
  • Community Events & Festivals: Participate in seasonal festivities and local gatherings that showcase the vibrant culture of this welcoming area, great for making family memories.
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Adult Activities

  • Historic Mayesville Walking Tour: Immerse yourself in the area's rich history by exploring historic sites and landmarks that tell the story of this charming destination.
  • Birdwatching at Lake Marion: Enjoy the tranquility of this natural spot while observing local bird species that thrive in the region's diverse ecosystem.
  • Fishing Excursions on Lake Marion: Spend a relaxing day casting your line in the well-stocked waters, perfect for anglers seeking leisure and adventure in here’s scenic environment.
  • Golfing at Regional Courses: Tee off at nearby golf courses designed to offer both challenging play and scenic views characteristic of the area’s landscape.

Mayesville Travel Tips

How Can You Make the Most of Your Stay?

  • Explore Local Dining Options: Take advantage of the region’s authentic eateries to enjoy traditional Southern flavors that showcase the area's culinary heritage.
  • Visit Nearby Natural Escapes: Discover scenic spots and peaceful outdoor spaces around here that provide a perfect backdrop for relaxation and outdoor activities.
  • Plan Your Transportation in Advance: Arrange reliable transportation options to easily access key attractions and make the most of your time in this destination.
  • Connect with the Community: Engage with local events or markets to experience the warm hospitality and culture that make here unique.

Transportation Options

  • Car Rentals: You can conveniently rent a vehicle in the area to explore nearby attractions and enjoy flexible travel around this charming destination.
  • Public Transit: Local bus services operate within the region, offering an economical way to navigate between key points of interest here.
  • Taxi Services: Reliable taxi companies are available for quick and private transportation, making it easy to get around without hassle.
  • Ridesharing Options: Rideshare services like Uber and Lyft provide on-demand transportation, giving you a convenient way to travel comfortably within the region.

Local Customs Options

  • Southern Hospitality:** Embrace the warm and welcoming spirit that is deeply rooted in the region, making your stay here feel like visiting a friendly community.
  • Local Festivals:** Participate in traditional celebrations and festivals that showcase the area's rich history and vibrant cultural heritage.
  • Gullah Heritage:** Discover the unique Gullah customs and traditions that are proudly preserved and celebrated in this part of South Carolina.
  • Cuisine Traditions:** Savor dishes influenced by longstanding Southern culinary practices, highlighting regional ingredients and cooking styles unique to here.

Mayesville Vacation Rental Frequently Asked Questions

2. How many vacation rentals have private pools in Mayesville?

There are 3 vacation rentals with private pools near Mayesville. Top-rated RBO homes that have access to a swimming pool include:

3. Which vacation homes in Mayesville are best for families?

If you are looking for a family-friendly vacation home in Mayesville, check out one of the following properties as all are highly-rated places to stay with excellent review for families or groups staying in Mayesville:

4. How many Rentbyowner vacation rentals are available in Mayesville?

Currently, the total number of properties listed by Rent By Owner in 2026 is over 83 in the Mayesville area, and still counting. By aggregating listings from multiple websites, Rent By Owner offers an immense amount of choice of the best RBO properties in Mayesville. 

5. What is the cancellation policy for vacation rentals in Mayesville, South Carolina?

The cancellation policy varies by property listing. You should review the specific rental's terms and conditions or contact the owner directly to understand the details before booking.

6. Are there any additional fees I should be aware of when booking a vacation rental in this part of South Carolina?

Additional fees such as cleaning fees, service charges, or security deposits are detailed on each property listing. Make sure to read the listing carefully or reach out to the owner for clarification.

7. How do I find the most suitable vacation rental for my stay in the area?

You can filter listings based on your preferred dates, amenities, and budget. Reviewing property descriptions and contacting owners for questions will help ensure you select the perfect rental for your visit.

8. What safety measures are in place at vacation rentals here during the current health climate?

Safety measures vary by property. Listings often include information about cleaning protocols and safety features. Contact the owner to confirm current practices and address any specific concerns.

9. How can I contact the property owner if I have questions about the vacation rentals in the region?

You can message the owner directly through the booking platform. Details for communication are available on each listing to assist you in making an informed reservation.

Mayesville Top Rated Vacation Rentals

9.2
Exceptional
(906 Reviews)
1 Bathroom
Family Friendly Hotel
  • Pool
  • Breakfast
  • Kitchen
US $220/Night For 7 Nights US $1,537
8.8
Fabulous
(724 Reviews)
1 Bathroom
Family Friendly Hotel
  • Pool
  • Breakfast
  • Kitchen
US $180/Night For 7 Nights US $1,262
8.8
Fabulous
(699 Reviews)
1 Bathroom
Family Friendly Hotel
  • Pool
  • Breakfast
  • Kitchen
US $137/Night For 7 Nights US $958
8.8
Fabulous
(145 Reviews)
2 Bathrooms
Ocean View Hotel
  • Oceanfront
  • Hot Tub
  • Fireplace/Heating
US $197/Night For 7 Nights US $1,379
8.6
Fabulous
(500 Reviews)
1 Bathroom
Family Friendly Hotel
  • Pool
  • Balcony/Terrace
  • Breakfast
US $205/Night For 7 Nights US $1,436
8.4
Excellent
(165 Reviews)
1 Bathroom
Family Friendly Hotel
  • Pool
  • Kitchen
  • Parking
US $150/Night For 7 Nights US $1,051
8.3
Excellent
(214 Reviews)
322.92 ft² 5 Bathrooms
Family Friendly Hotel
  • Private Pool
  • Fireplace/Heating
  • Pool
US $166/Night For 7 Nights US $1,162
8.3
Excellent
(68 Reviews)
415.18 ft² 1 Bathroom
Free Cancellation Hotel
  • Private Pool
  • Fireplace/Heating
  • Pool
US $194/Night For 7 Nights US $1,356