Discover Your Perfect Panama Vacation Homes

Best Vacation Homes in Panama

New
1500 ft² 8 Guests 3 Bedrooms 2 Bathrooms
Family Friendly Condo
  • Hot Tub
  • Fireplace/Heating
  • Balcony/Terrace
US $937/Night For 7 Nights US $6,561
10.0
Exceptional
(2 Reviews)
1905.21 ft² 8 Guests 4 Bedrooms 2 Bathrooms
House
  • Pet Friendly
  • Parking
  • Internet
US $312/Night For 7 Nights US $2,184
9.6
Exceptional
(54 Reviews)
1 Bedroom 1 Bathroom
Family Friendly Bed & Breakfast
  • Fireplace/Heating
  • Breakfast
  • Parking
US $133/Night For 7 Nights US $931
10.0
Exceptional
(82 Reviews)
855 ft² 4 Guests 2 Bedrooms 1 Bathroom
Family Friendly House
  • Fireplace/Heating
  • Balcony/Terrace
  • Kitchen
US $128/Night For 7 Nights US $898
10.0
Exceptional
(1 Review)
2206.6 ft² 6 Guests 2 Bedrooms 3 Bathrooms
House
  • Spa
  • Fireplace/Heating
  • Parking
US $199/Night For 7 Nights US $1,391
10.0
Exceptional
(72 Reviews)
3000 ft² 16 Guests 5 Bedrooms 2 Bathrooms
Family Friendly House
  • Fireplace/Heating
  • Balcony/Terrace
  • Kitchen
US $433/Night For 7 Nights US $3,033
10.0
Exceptional
(64 Reviews)
1700 ft² 8 Guests 3 Bedrooms 2 Bathrooms
Family Friendly House
  • Fireplace/Heating
  • Balcony/Terrace
  • Pet Friendly
US $247/Night For 7 Nights US $1,729
10.0
Exceptional
(59 Reviews)
4 Guests 1 Bedroom 1 Bathroom
Family Friendly Condo
  • Fireplace/Heating
  • Pet Friendly
  • Kitchen
US $153/Night For 7 Nights US $1,069

Panama Luxury Rentals

New
6 Guests 2 Bedrooms 1 Bathroom
Pet Friendly RV Rental
  • Pool
  • Pet Friendly
  • Air Conditioner
Unlock the Best Price
10.0
Exceptional
(2 Reviews)
8000 ft² 22 Guests 9 Bedrooms 7 Bathrooms
Family Friendly Bed & Breakfast
  • Fireplace/Heating
  • Breakfast
  • Kitchen
US $1,606/Night For 7 Nights US $11,239
9.8
Exceptional
(46 Reviews)
20 Guests 6 Bedrooms 5 Bathrooms
Family Friendly Apartment
  • Fireplace/Heating
  • Balcony/Terrace
  • Kitchen
US $1,404/Night For 7 Nights US $9,825
9.8
Exceptional
(7 Reviews)
5500 ft² 18 Guests 5 Bedrooms 3 Bathrooms
Ocean View House
  • Private Pool
  • Hot Tub
  • Fireplace/Heating
US $1,319/Night For 7 Nights US $9,232
9.2
Exceptional
(13 Reviews)
12 Guests 6 Bedrooms 3 Bathrooms
Family Friendly House
  • Fireplace/Heating
  • Balcony/Terrace
  • Kitchen
US $1,038/Night For 7 Nights US $7,268
10.0
Exceptional
(8 Reviews)
4000 ft² 20 Guests 5 Bedrooms 3 Bathrooms
Family Friendly House
  • Hot Tub
  • Fireplace/Heating
  • Balcony/Terrace
US $889/Night For 7 Nights US $6,225
10.0
Exceptional
(9 Reviews)
4200 ft² 12 Guests 4 Bedrooms 3 Bathrooms
Pet Friendly House
  • Hot Tub
  • Fireplace/Heating
  • Pet Friendly
US $775/Night For 7 Nights US $5,424
New
8 Guests 4 Bedrooms 2 Bathrooms
Family Friendly House
  • Parking
  • Child Friendly
  • Security/Safety
US $669/Night For 7 Nights US $4,685

Panama Pet Friendly Vacation Rentals

10.0
Exceptional
(50 Reviews)
825 ft² 6 Guests 2 Bedrooms 1 Bathroom
Family Friendly House
  • Fireplace/Heating
  • Balcony/Terrace
  • Pet Friendly
US $184/Night For 7 Nights US $1,289
9.8
Exceptional
(32 Reviews)
495.14 ft² 2 Guests 1 Bedroom 1 Bathroom
Free Cancellation Villa
  • Fireplace/Heating
  • Pet Friendly
  • Parking
US $111/Night For 7 Nights US $774
8.4
Excellent
(10 Reviews)
4 Guests 1 Bedroom 1 Bathroom
Family Friendly House
  • Fireplace/Heating
  • Pet Friendly
  • Kitchen
US $152/Night For 7 Nights US $1,061
10.0
Exceptional
(38 Reviews)
1108 ft² 6 Guests 2 Bedrooms 2 Bathrooms
Family Friendly Condo
  • Fireplace/Heating
  • Balcony/Terrace
  • Pet Friendly
US $274/Night For 7 Nights US $1,919
8.4
Excellent
(7 Reviews)
1001.04 ft² 5 Guests 2 Bedrooms 1 Bathroom
House
  • Fireplace/Heating
  • Pet Friendly
  • Parking
US $117/Night For 7 Nights US $821
10.0
Exceptional
(14 Reviews)
2 Guests 1 Bedroom 1 Bathroom
Family Friendly Cottage
  • Fireplace/Heating
  • Balcony/Terrace
  • Pet Friendly
US $132/Night For 7 Nights US $923
10.0
Exceptional
(12 Reviews)
7 Guests 3 Bedrooms 2 Bathrooms
Family Friendly Cottage
  • Fireplace/Heating
  • Pet Friendly
  • Kitchen
US $166/Night For 7 Nights US $1,163
10.0
Exceptional
(10 Reviews)
4 Guests 2 Bedrooms 1 Bathroom
Family Friendly Apartment
  • Fireplace/Heating
  • Balcony/Terrace
  • Pet Friendly
US $126/Night For 7 Nights US $880

Panama Large Vacation Homes

10.0
Exceptional
(34 Reviews)
11 Guests 4 Bedrooms 3 Bathrooms
Family Friendly House
  • Fireplace/Heating
  • Balcony/Terrace
  • Kitchen
US $574/Night For 7 Nights US $4,020
10.0
Exceptional
(1 Review)
1829.86 ft² 10 Guests 3 Bedrooms 2 Bathrooms
House
  • Fireplace/Heating
  • Parking
  • Internet
US $195/Night For 7 Nights US $1,365
10.0
Exceptional
(33 Reviews)
3600 ft² 12 Guests 4 Bedrooms 2 Bathrooms
Family Friendly Condo
  • Hot Tub
  • Fireplace/Heating
  • Balcony/Terrace
US $651/Night For 7 Nights US $4,557
9.5
Exceptional
(92 Reviews)
1052.71 ft² 47 Guests 21 Bedrooms 16 Bathrooms
Bed & Breakfast
  • Fireplace/Heating
  • Balcony/Terrace
  • Parking
US $155/Night For 7 Nights US $1,085
10.0
Exceptional
(26 Reviews)
10 Guests 4 Bedrooms 3 Bathrooms
Family Friendly House
  • Fireplace/Heating
  • Balcony/Terrace
  • Kitchen
US $318/Night For 7 Nights US $2,224
10.0
Exceptional
(8 Reviews)
12 Guests 5 Bedrooms 3 Bathrooms
Family Friendly House
  • Fireplace/Heating
  • Balcony/Terrace
  • Pet Friendly
US $393/Night For 7 Nights US $2,750
10.0
Exceptional
(7 Reviews)
1744 ft² 10 Guests 4 Bedrooms 2 Bathrooms
Family Friendly House
  • Fireplace/Heating
  • Balcony/Terrace
  • Kitchen
US $451/Night For 7 Nights US $3,159
10.0
Exceptional
(6 Reviews)
10 Guests 5 Bedrooms 3 Bathrooms
Family Friendly House
  • Fireplace/Heating
  • Balcony/Terrace
  • Kitchen
US $561/Night For 7 Nights US $3,929

Why Choose Rent By Owner for your Panama Vacation Rental Homes?

What makes our Vacation Rentals special?

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Verified Listings
Book with confidence knowing every property meets our quality and safety standards.
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Unbeatable Value
Enjoy competitive pricing with no hidden fees, providing exceptional value for every stay.
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Diverse Options
From cozy cabins to luxurious villas, find a rental that suits your style and needs.

Best Times to Visit Panama

When should you plan your Vacation Rentals stay?

Timing your visit to this destination can enhance your experience, so consider planning your stay during the region's most favorable seasons for weather and local events.

Peak Season Highlights

summer
Summer (June to August)

During the warm summer months, you can enjoy ideal weather for outdoor activities and exploring the region. This is when tourism peaks, so booking early ensures access to the best vacation rentals here.

Average Temperature Daytime: 85°F - Nighttime: 65°F
autumn
Fall (September to November)

In early fall, the area experiences mild temperatures and fewer crowds, making it a great time to enjoy scenic views and local events. Securing your rental early guarantees a comfortable stay during this popular season.

Average Temperature Daytime: 75°F - Nighttime: 55°F

Off-Season Highlights

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Winter (December to February)

The winter months bring cooler temperatures, with fewer visitors staying in vacation rentals here. It’s an ideal period if you prefer a quieter experience and lower rates on accommodations.

Average Temperature Daytime: 45°F - Nighttime: 25°F
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Spring (March to May)

Early spring offers milder weather before the peak season begins, providing a peaceful atmosphere and affordable rates for your stay. This is a good time to find deals on your vacation rentals in the region.

Average Temperature Daytime: 65°F - Nighttime: 45°F

Weekly Weather Forecast for Panama

Booking Steps

01

Search Properties

Use our filters to find the right property that fits your needs.
02

Select a Rental

Click on your preferred listing to view details, amenities, and pricing.
03

Book Online

Follow the link to finalize your reservation directly on the partner’s website.

Indoor Features

  • Fully-equipped kitchens with modern appliances
  • Comfortable living areas with flat-screen TVs
  • Free Wi-Fi for staying connected
  • Air conditioning and heating for year-round comfort
  • In-unit washers and dryers for convenience
  • Luxurious bedrooms with premium bedding
  • Spa-like bathrooms with soaking tubs or walk-in showers

Outdoor Amenities

  • Enjoy outdoor seating areas such as patios or decks to relax and take in the scenic views.
  • Benefit from spacious yards or gardens perfect for outdoor activities or simply unwinding in the fresh air.
  • Take advantage of on-site grilling facilities to prepare delicious meals amidst the natural surroundings.
  • Access private or shared outdoor pools to cool off during warm days here in the region.
  • Make use of designated fire pits or fireplaces ideal for evening gatherings and roasting marshmallows.
  • Explore nearby hiking or walking trails that offer a chance to discover the beauty of this destination’s outdoors.
  • Utilize outdoor recreational amenities such as volleyball courts, horseshoe pits, or basketball hoops to stay active during your stay.
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Family Activities

  • Panama Canal Observation Center: Spend time here to watch ships traverse the iconic canal and learn about its engineering marvels, making it a memorable family activity in this region.
  • Miraflores Locks Visitor Center: Experience the excitement of watching boats pass through the locks while exploring informative exhibits that highlight the area's significance in global shipping.
  • Gatun Lake Boat Tours: Enjoy a scenic boat tour on the lake, offering your family an engaging way to appreciate the natural beauty and history of this destination's waterways.
  • Panama Old Town (Casco Viejo): Discover the charm of historic streets, colorful architecture, and vibrant plazas that provide a culturally enriching experience for families visiting the area.
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Adult Activities

  • Exploring Lake Maloney State Recreation Area: You can enjoy a relaxing day of fishing, boating, or picnicking at this beautiful local outdoor spot, perfect for unwinding in nature.
  • Visiting the Pioneer Museum: Delve into regional history and learn about the area's rich heritage through engaging exhibits and preserved historic artifacts.
  • Golfing at the nearby courses: Challenge yourself on well-maintained golf courses that offer scenic views and a relaxing atmosphere just minutes from your stay.
  • Discovering local dining scenes: Savor delicious regional cuisine at nearby restaurants that showcase the flavors unique to this destination’s community and culture.

Panama Travel Tips

How Can You Make the Most of Your Stay?

  • Plan Ahead for Local Events: Check the area's event calendar to align your stay with local festivals or activities that showcase the region's culture and charm.
  • Explore Nearby Natural Spots: Take advantage of the region's scenic landscapes by visiting nearby parks or trails to experience its natural beauty firsthand.
  • Utilize Local Resources: Reach out to hosts or local visitor centers for insider tips on hidden gems and the best spots to visit during your stay.
  • Optimize Your Travel Timing: Consider visiting during shoulder seasons for fewer crowds and more affordable rates on your vacation rentals here.

Transportation Options

  • Panama Bus Station: This regional hub offers convenient bus services connecting you to nearby cities and states, making local travel straightforward.
  • Personal Vehicles: Having your own car provides the flexibility to explore the area at your own pace and access remote spots around Panama, Nebraska.
  • Taxi Services: Licensed taxis are readily available for quick trips within the region, ensuring comfortable and reliable transportation options during your stay.
  • Rental Cars: Car rental agencies in the vicinity provide a range of vehicles suitable for exploring both here and beyond with ease and convenience.

Local Customs Options

  • Local Dining Etiquette: In this region, sharing meals and engaging in friendly conversation are valued customs that enhance your experience when enjoying local cuisine through nearby vacation rentals.
  • Community Festivals: Participating in annual community festivals fosters a sense of belonging and provides a unique opportunity to experience authentic regional traditions right here in the area.
  • Respect for Nature: Environmental consciousness is important in this destination, so it’s customary to dispose of waste properly and respect local parks and natural sites during your stay.
  • Greeting Traditions: A warm handshake or a friendly nod is typical when meeting locals, reflecting the welcoming spirit you’ll encounter throughout your visit.

Panama Vacation Rental Frequently Asked Questions

2. How many vacation rentals have private pools in Panama?

There are 19 vacation rentals with private pools near Panama. Top-rated RBO homes that have access to a swimming pool include:

3. Which vacation homes in Panama are best for families?

If you are looking for a family-friendly vacation home in Panama, check out one of the following properties as all are highly-rated places to stay with excellent review for families or groups staying in Panama:

4. How many Rentbyowner vacation rentals are available in Panama?

Currently, the total number of properties listed by Rent By Owner in 2026 is over 421 in the Panama area, and still counting. By aggregating listings from multiple websites, Rent By Owner offers an immense amount of choice of the best RBO properties in Panama. 

5. What is the cancellation policy for vacation rentals near Panama in Nebraska?

Cancellation policies vary by listing, so it’s important to review the specific terms on the property’s page or contact the owner directly before booking.

6. How do I find pet-friendly vacation rentals in this area?

To locate pet-friendly options, use the filters available on the booking website and check the property details for any specific pet policies or restrictions.

7. Are there any additional fees I should be aware of when booking a rental here?

Additional fees such as cleaning fees or security deposits are typically listed in the property details; always review these before finalizing your reservation.

8. Can I see reviews from previous guests before booking a vacation rental?

Yes, reviews are available on each property listing and can help you gauge the quality and suitability of the rental for your stay.

9. What amenities are usually included in vacation rentals in this region?

Amenities vary by property but commonly include essential comforts such as Wi-Fi, parking, and kitchen facilities; detailed information can be found in each listing.

Panama Top Rated Vacation Rentals

9.8
Exceptional
(12 Reviews)
8 Guests 2 Bedrooms 2 Bathrooms
Family Friendly Apartment
  • Fireplace/Heating
  • Pool
  • Pet Friendly
US $338/Night For 7 Nights US $2,363
9.7
Exceptional
(27 Reviews)
346.24 ft² 18 Bathrooms
Ocean View Hotel
  • Private Pool
  • Oceanfront
  • Hot Tub
US $167/Night For 7 Nights US $1,171
9.6
Exceptional
(1001 Reviews)
1 Bathroom
Family Friendly Hotel
  • Hot Tub
  • Fireplace/Heating
  • Pool
US $147/Night For 7 Nights US $1,031
9.6
Exceptional
(157 Reviews)
1 Bathroom
Family Friendly Hotel
  • Hot Tub
  • Fireplace/Heating
  • Pool
US $139/Night For 7 Nights US $976
9.6
Exceptional
(60 Reviews)
1 Bathroom
Family Friendly Hotel
  • Fireplace/Heating
  • Pool
  • Breakfast
US $142/Night For 7 Nights US $993
9.4
Exceptional
(659 Reviews)
1 Bathroom
Family Friendly Hotel
  • Hot Tub
  • Pool
  • Balcony/Terrace
US $162/Night For 7 Nights US $1,131
9.4
Exceptional
(421 Reviews)
538.19 ft² 17 Bathrooms
Free Cancellation Hotel
  • Oceanfront
  • Hot Tub
  • Fireplace/Heating
US $199/Night For 7 Nights US $1,393
9.4
Exceptional
(360 Reviews)
1 Bathroom
Family Friendly Hotel
  • Fireplace/Heating
  • Pool
  • Balcony/Terrace
US $127/Night For 7 Nights US $892